Answers were Sorted based on User's Feedback
Answer / bujji kanchi
1)inject same concentration of impurity and active
Ratio of impurity area and active area
correct the concentrations.
Best practice is
Inject LOQ to 150% of specification around 5 levels
and calculate the slope of impurity and slope of active
take the slpe ratio.
|Is This Answer Correct ?||8 Yes||0 No|
Answer / javed
RRF Can be calculated by comparing the area of standard with
area of impurity x conc of imp by conc of std x 100.
|Is This Answer Correct ?||9 Yes||8 No|
What is the requirement for brazil in the analytical method vslidation comparr to ich?
hii, i'm had a sample of 1L that gone through extraction & evaporation. i used 0.5ml of methanol for reconstitution before injecting the sample to HPLC. i made a calibration curve using a standard solution but now i'm confused about how to display the concentration i got from the sample. for ex. i got 0.2ug/ml how i'm gonna explane this is for the 1L ? please help .. i'll really appreciate it thanks
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