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HOW RRF IS CALCULATED IN HPLC
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Answer / bujji kanchi
1)inject same concentration of impurity and active
Ratio of impurity area and active area
correct the concentrations.
Best practice is
Inject LOQ to 150% of specification around 5 levels
and calculate the slope of impurity and slope of active
take the slpe ratio.
Regards,
Bujji Kanchi.
| Is This Answer Correct ? | 8 Yes | 0 No |
Answer / javed
RRF Can be calculated by comparing the area of standard with
area of impurity x conc of imp by conc of std x 100.
| Is This Answer Correct ? | 9 Yes | 8 No |
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