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Analytical Chemistry Interview Questions
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in dissolution in one tablets two molecule one is losartan & second is HCTZ losartam is complies in s1 stage & hctz is complies in s2 stage then how to report result losartan s1 stage result or losartan s2 stage result

Dishman,

1 1241

why we use polystyrene film for ftir calibration?

Rakshit Drugs,

4 14225

WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

GVK,

1688

why do we adjusted ph in the mobilphase

Cipla, Dr Reddys, Reddy Labs,

9 18674

How to develop the method when we have very low amount of impurity?

2 6308

If we have 120 minutes run time method for HPLC and you wan to decrease the Run time so what should you do??

 6 9868

Wath is the differenc between two column HPLC wich have the samme support , lenth , pore size, etc.. But different name .for exemple : Spherisorb / lichrosorb

NDA,

2 5963

WHAT IS PVT TEST IN DISSOLUTION TEST , WHAT IS PVT SIGNIFICANCE AND HOW IT IS PERFORMED ?

 1 5867



 1362

How you will select column for HPLC development depends on nature of compound and how it will work explain in brief?

 3 7937

What is the role of SO2,I2, Methanolic hydroxide and any base in Karlficher titration

Medley Pharmaceuticals,

2 6816

The boiling point of 1,3 butadiene is -4.4 DC & the boiling point of Pentane is 36.1 DC. Then how come Pentane elute before 1,3 BD in GC analysis?

 1 3701

What is Arsenic Test?

Flamingo Pharmaceuticals,

1518

What is the difference between Optical rotation and Spcefic optical rotation

IPCA, Matrix,

2 10548

why we use sodium salicylate in uv light calibration at TLC chamber

Aurobindo, Lee Pharma,

1 6153

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Un-Answered Questions { Analytical Chemistry }

In Dissolution Test why limit is define Q+5% what is the role of +5%.

1941

What is intact assay method development.....?

1468

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

2526

How can the GC or HPLC method is selected to determine the impurity profile in drug product?

6027

we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

790




why octanol used to determine the partition coefficient ?

1351

What is importance of pH in the Heavy metal test and How it effect on the test results?

1285

If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

1272

Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

1699

WHY pKa value is more important than pH value of the mobile phase in HPLC?

666

In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

2245

Colorimtry

629

What should be the level/ Percentage of Arsenic in Arsenic free zinc.

1325

how the compound separate in coulunm,explain

1387

How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium

1404

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