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hii, i'm had a sample of 1L that gone through extraction & evaporation. i used 0.5ml of methanol for reconstitution before injecting the sample to HPLC. i made a calibration curve using a standard solution but now i'm confused about how to display the concentration i got from the sample. for ex. i got 0.2ug/ml how i'm gonna explane this is for the 1L ? please help .. i'll really appreciate it thanks
1 4216Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me
5 9729some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
2653When ever we perform system suitability,inject the corresponding standard 6 times why? is thair any reson
4 10736Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?
29631)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.
2885
what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me
In rs method development when we are going area normalization method to dilute standard method?
Is it nessesary all multimedia dissolution require descriminatory?
Difference between hlaf and rlaf
In order to avoid the pyridine catalyst use in many synthesis which is harmfull to environment, which catalyst can be used....?
Explain the function of a monosaccharide?
what is the difference between potentiometric titration and karl fischer titration?
Define chemical corrosion. What are the types of chemical corrosion? : Electrochemistry Corrosion
What is the hybridization at nitrogen?
A polymer's structure influences its physical properties. Describe two structural variations that are possible for polypropylene but not for polyethylene. : Polymer Chemistry
Is benzene aromatic?
What is the accepted microbial load in APIs as per USP.........?
about method developement in hplc
What is the range of uv & vis lamp in spectrophotometer?
if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?
