can we Consider the Purity threshold and Purity angle in place of peak purity for the specificity test for method verification
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Answer / Aditya Kumar Nigam
In general chemistry, the peak purity is a valuable tool for identifying compounds during chromatography. However, if a purity threshold (usually expressed as a percentage) and purity angle (often used in 2D chromatography) can reliably demonstrate the identity of the compound based on the context of your method verification, then it may be acceptable to use them as alternatives to peak purity. Consult with your lab's SOPs or a chemist for specific guidance.
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