Interested to Buy Any Domain ? << Click Here >> for more details...
what is end capping in hplc coulmn
- 2 Answers
- 12878 Views
- Lupin, Zydus Cadila, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / kiran ambekar
Capping of exposed silanol with short chain HC chain
ie.Trimethyl chlorosilane.
Now a day all columns are end capping.
generally End capping column is used for basic compounds
for reducing the peak tailing
| Is This Answer Correct ? | 23 Yes | 3 No |
Answer / r.kadambavadani
In chromatography, endcapping refers to the replacement of accessible silanol groups in a bonded stationary phase by trimethylsilyl groups.
Endcapping technology prevents the tailing of a polar compound's peak and shows very high durability even with an alkaline mobile phase because of the strong film covering the stationary phase surface.
| Is This Answer Correct ? | 1 Yes | 0 No |
When i inject amines and acid on HPLC then which peak will elut first?
difference between precision & accuracy.
why did uyou choose analytical chemistry?
What is the thickness of polystyrene film?
8 Answers Pharmaffiliates Analytics and Synthetics,
class of solvent regarding Residual solvent e.g. Acetone his class
what is full form of RVT
why we inject sample TWICE in ASSAY by HPLC analysis but in RS once?
4 Answers Aurobindo, DRL, Neuland,
Give me details about dissolution , with name ?
Why Peak Purity is not determined in GC analysis?
what is specificity?
4 Answers Amneal Pharmaceuticals, Aurobindo,
in stress study if your api not soluble in hcl naoh h2o2 then what require to do?
Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc
Organic Chemistry 
