in pentoperazole capsules usp why assay value is substract
from dissolution
Answer / dnyaneshwar
In case of Pentaprazole Enteric coated Tablet,As per USP ( % Released at Acid stage = Assay - Content after acid stage ).
Solution : Petaprazole molecules is very unstable in 0.1 M HCl i.e highly degraded.At the time of acid stage dissolution,the release of pentaprazole will start to degrade very fastly.Release & degradation rate take place simultaneously.Thus to determine actual released at acid dissolution after 2 hrs we can determine by above formula
| Is This Answer Correct ? | 0 Yes | 0 No |
Why we use potassium dichromate in uv calibration Exact reason behind it??
how we can identify the impurity is coming below loq at transfering site?
In acid base titration, after complet consumption of HCl by NaOH, addition of next drop of NaOH will give pink colour with phenolpthalein indicator. Why this pink colour appear? Why not blue, black, green or anything elese?
What is the purpose of octyl silane columns?
How to decide restandardisation due or retest or expiry of Volumetric solutions prepared in wet chemistry lab?
wat is the role of michelson interferometer in FTIR and He-Ne lase.detailed answer required in simple language
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
0 Answers Petronas, Shanghai Ocean University,
[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?
why peak purity not considered in GC?
4 Answers DRL, Reddy Labs, Vimta Labs,
What should be the precision for HPLC during technology transfer?
in pentoperazole capsules usp why assay value is substract from dissolution