Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

How to calculate the signal to noise ratio.

Rakshit Drugs,

1 4700

Why pH range is 1-14 nt more than 14???

IPCA, Lincoln Pharmaceuticals,

3 5340

Weight balance variation limit during analysis

Amneal Pharmaceuticals,

7 4531

How to calculate lamp energy in hplc?


Difference between related substances & impurities


1 7168

Polarized meter calibration, 1. Method name? 2. Which solution use? 3.why?

1 1818

Basic principle of ESI?

Cipla, GVK,


What is the meaning of Base deactivated vials

Sun Pharma,

1 1178

What is definition of RRT and what is the difference between RT and RRT in HPLC

1 3297

What is the definition of RRF

2 3788

In GC Why does retention time decrease when temperature increases? Also how does a change in temperature effect selectivity?

Gland Pharma,

1 1389

why we use 0.1% acetone in gradient calibration of HPLC?

FDC, Dr Reddys, Cipla,

2 6194

What is difference between assay by Hplc and uv

Aizant, Fredun Pharmaceuticals, Hetero, Marksans Pharma,

2 5688

why we use actone for Gpv test in hplc calibration

1 5519

How to standardization of 1N H2SO4?

GNFC, Macleods,

1 4418

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Un-Answered Questions { Analytical Chemistry }

We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?


What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio


Why potassium dichromate was using in Uv calibration?


how can I make the copper get white bye any salt or acit?


If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?


what is third integration


please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.


In Dissolution Test why limit is define Q+5% what is the role of +5%.


What should be the level/ Percentage of Arsenic in Arsenic free zinc.


What is Band broading effect explain


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?


In Karl Fischer titration,What is the situation if the material tested is only soluble in water,and not soluble in the common solvents used such as methanol ?? [e.g. Iron III Hydroxide polymaltose]