Advantage of Update Panel over Asp.net 2.0 + C#+ Microsoft
Ajax 1.0
AJAX is a client side technology and it supports asynchronous communication between client and server. If the part of page need to be refreshed, then we can use this Update panel control, which uses AJAX request and does not harm the other part of the page. Please refer below link for more details
https://csharpquestions1.blogspot.in/2016/10/why-to-use-updatepanel-control-in-ajax.html
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