poly-L- vs. poly-D-lisine ?



poly-L- vs. poly-D-lisine ?..

Answer / Azra Firdaush

Poly-L-lysine and poly-D-lysine are both linear polymers of lysine, an amino acid, but they differ in their optical isomerism: Poly-L-lysine has the L configuration while poly-D-lysine has the D configuration. In cell culture, poly-L-lysine is commonly used as a coating for tissue culture plates and glass slides to enhance adhesion of negatively charged cells such as mammalian cells due to its positive charge.

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