Answer / Navaneet Kumar Singh

The direction of a nucleotide substitution (for example, C to T or T to C) is determined by comparing the DNA sequences before and after the mutation. If the base at the mutated position in the new sequence differs from the original sequence, it indicates the direction of the substitution.

In Reimer-Tiemann?s reaction, the reaction intermediate is (a) Carbene (b) Dichloro carbene (c) Carbonion (d) Carbonium ion.

1 Answers   Biotech, Wipro,

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In the next two or three years what will the important advances in the field be?

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How long will a train 100m long traveling at 72kmph take to overtake another train 200m long traveling at 54kmph?

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Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ user sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?

4 Answers   Infosys,

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What is the main idea of maximum parsimony in phylogenetic tree construction? What are the drawbacks?

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What are oesophageal molecular markers?

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Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ User sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?

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A man speaks the truth 3 out of 4 times. He throws a die and reports it to be a 6. What is the probability of it being a 6?

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What is Proteomics?

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Select the correct statements (a) A simple harmonic motion is necessarily periodic (b) An oscillatory motion is necessarily periodic (c) A periodic motion is necessarily oscillatory (d) All of the above.

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Suppose the Blast search returned 100 hits. Of these, 17 were false positives and we knew that there were 165 sequences in the database which should have returned a hit with our sequence. How many false negatives were there, and what is the sensitivity and selectivity of Blast in this instance?

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All toffees are chocolates. Some toffees are not good for health. (a) Some chocolates are not good for health (b) Some toffees are good for health (c) No toffees are good for health (d) Both (a) and (b).

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