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What are the common features of active site?

What are the common features of active site?..

Answer / meyyappa

The active site occupies a relatively smallportion of the
enzyme molecule.

the active site is neither a point nor a line or even a
plane but it is a 3 dimensional entity.

it is made up of groups that come from different parts of
linear aminoacid sequence.

the arrangement of atoms is well defined resulting in
marked specificity of the enzymes.

Active site binds substrate molecule by relatively weak

Active sites in enzyme molecules are grooves from which
water is largely excluded.

It contains aminoacids such as aspatic acid,glutamic
acid,lysine,serine etc.side chain groups like -COOH,-NH2,-
CH2OH serve as catalytic groups in the active site.

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