At what distance the sample is collected in dissolution
basket?
Answers were Sorted based on User's Feedback
Answer / sameer joshi
as per usp sample aliquots should withdrawn abut middle
height from basket and dissolution media level and 1cm away
from side wall of the jar.
Is This Answer Correct ? | 15 Yes | 0 No |
Answer / praveen vyas
As per usp sample should be drawn from middle of the basket or paddle upper surface and dissolution medium level and 1 cm away from jar wall
Is This Answer Correct ? | 1 Yes | 0 No |
please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
what is reverse phase chromarography&normal phase chromatography
difference between HPLC & LC-MS
I got 88.0 % assay for a drug in HPLC analysis for same injection i got 40.0% related substances is it possible? what is the relation between results of assay and purity?
why ph is between 0 to 14
6 Answers Apotex, Reliance, Zydus Cadila,
Why we are having specification 100% above in case of assay as there is only 100% of compound?
2 Answers MSN Pharma, Nectar Lifesciences,
What is the reason for using the 900ml of dissolution medium
why we are using k2cr207 in uv calibration ? why we r not using kmno4?
1 Answers Glochem, Sidmak Laboratories,
what are the different methods of analysing related substances test,what are LOD AND LOQ .HOW TO REPORT IMPURITIES WHEN LOD AND LOQ LIMITS R SPECIFIED
I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?
how much you expected salary?
7 Answers GSK GlaxoSmithKline,
If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?