Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

WHY pKa value is more important than pH value of the mobile phase in HPLC?

547

Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

420

For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

416

In Assy by potentio metry titration method how select MET U ,DET U, SET U,

476

in sampling of raw material which side is pasted sampled labels

502

why holium oxide prepared in 10% HCLO4 SOLUTION

374

Why 162 mg NaOH used for 1N volumetric solution in 150 ml water then 54.5 ml diluted with 1000 ml

576

What is the importance of rrf in rs by HPLC?

1 1077

Why use only methanol,used determinationof moisture content not use other solvents

163

please explain about aluminium hydroxide assay

156

How to know the estimated LOQ concentration in ppm

135

What is the difference between c8 and c18 hplc column?

120

Why karl fisher factor is 5 ?

1 183

Loss of linearity in tkn analysis, possible reasons?

105

In rs method development when we are going area normalization method to dilute standard method?

152


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Un-Answered Questions { Analytical Chemistry }

USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

844


What is similarity factor and its use in api strength?

129


What is intact assay method development.....?

1398


What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

7176


why we are using benzene, anyline in acetic anhdride assay titration method?

1063






what is the procedure for cleaning of lenses of hatr accesory of ftir instrument?

1318


What is the main difference between ODS1 and ODS2 Hplc column.

2902


Difference between hlaf and rlaf

971


What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?

2920


Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?

1191


How do we fix the sample concentaryion in hplc method development?

107


when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

997


What is third generation HPLC Columns?

983


what is definition of validation? which components are followed give detail?

1151


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

1479