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please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
1632How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?
1779Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...
1691In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
1973Post New Analytical Chemistry Questions
What is the Formula for coreletion coefficient in plhplc calibration
How you develop a method in HPLC?
what is the difference between potentiometric titration and karl fischer titration?
What is the difference between purge septum flow and column flow in gas chromatography?
if rsd failed then what require to do?
If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?
Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?
What is mean by PDR?
how you start the solubility study?
why does used dry caffien in HPLC calibration?
why octanol used to determine the partition coefficient ?
how to select short coloum and long coloumn for new molecule
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
Why we use potassium dichromate in uv calibration Exact reason behind it??
What is similarity factor?
