please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development273
How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?268
How can we calculate offset value pH measurment148
What is stray light in uv what are units for stray light173
What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio239
Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...182
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?254
How to check hplc detecter sensitivity?184
what is the structure of DOWEX-50
WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE
Which std. used for standrdisation of ZnSO4?
calibrtion procedue of LC-MS
In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )
How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.
why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?
what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?
what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.
Why to use propyl paraben in HPLC gradient calibration
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
In performance Check of GC Why Hexadecane Peak is Considered
WHAT IS DIFFERENCE B/W MALTINGRANG/DSC
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.