Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

Pfizer,

451

How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

510

How can we calculate offset value pH measurment

Dr Reddys,

325




What is stray light in uv what are units for stray light

Dr Reddys,

377

Colorimtry

Dr Reddys,

343

What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio

Dr Reddys,

462

What are usp limits for total impurities,unknown impurity

Dr Reddys,

1 1233

how to get accurate result for Residue on evaporation in purified water

439




Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

422

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

479

could negative ions be produced by bombardment process in mass spectrometry?

344

A ha tc is actual defination of retention time?

351

How to check hplc detecter sensitivity?

Gland Pharma,

381

(0.41)d what is d?

Gland Pharma,

1 745

How to estimate potassium?

1 437


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Un-Answered Questions { Analytical Chemistry }

How much is the standard area for glc analysis

1072


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

1285


explain 5 components of gas chromatography ?

786


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

850


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1200






Why to use propyl paraben in HPLC gradient calibration

1302


Qc interview questions

520


How to know the estimated LOQ concentration in ppm

1


what is partion and column chromatography

1153


Why perchloric acid used for potentiometric titration

1441


EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE

1463


What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio

462


In Karl Fischer titration,What is the situation if the material tested is only soluble in water,and not soluble in the common solvents used such as methanol ?? [e.g. Iron III Hydroxide polymaltose]

1647


which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

1071


As per ICH related substances stability trend limit from initial to shelf life

1922