Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

Pfizer,

308

How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

315

How can we calculate offset value pH measurment

Dr Reddys,

185




What is stray light in uv what are units for stray light

Dr Reddys,

219

Colorimtry

Dr Reddys,

204

What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio

Dr Reddys,

283

What are usp limits for total impurities,unknown impurity

Dr Reddys,

1 570

how to get accurate result for Residue on evaporation in purified water

258




Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

225

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

292

could negative ions be produced by bombardment process in mass spectrometry?

177

A ha tc is actual defination of retention time?

206

How to check hplc detecter sensitivity?

Gland Pharma,

221

(0.41)d what is d?

Gland Pharma,

1 413

How to estimate potassium?

1 214


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Un-Answered Questions { Analytical Chemistry }

We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?

245


when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

759


what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?

2277


What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?

2472


How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

2400






What is importance of pH in the Heavy metal test and How it effect on the test results?

942


why does used dry caffien in HPLC calibration?

564


what is difference between zero air gas and o2 gas

6068


Did anybody have method for acetyl cysteine effervescnce tablet

876


How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?

1821


As per ICH related substances stability trend limit from initial to shelf life

1700


pharma industries oriented

825


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.

684


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

677


We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

162