How can i do the Homology Modeling of GPCR receptor
successfully? My target identity with template is only 27%
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Answer / ravi pawar
u cant do homology modellling bez ur target identity with
template is only 27% ,for homology modellling identity
should be 30% or more ...you have to go for comparative
modelling .
| Is This Answer Correct ? | 8 Yes | 0 No |
Answer / jomy peter thomas
homology modeling is actually comparitive modeling.
so threading is the best option..
| Is This Answer Correct ? | 2 Yes | 0 No |
Answer / g.s.mohana
u can do Ab-initio modeling, bcoz for homology modelling u need to have >40%similarity with template and target sequence.to perform Ab-initio modeling u can use ITASSER online tool.
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / abhi
with this much one option is to go for threading
second option is to break ur seq into some pieces and then
search template for all the fragmants definately this will
help u ...............
| Is This Answer Correct ? | 2 Yes | 6 No |
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