How can i do the Homology Modeling of GPCR receptor
successfully? My target identity with template is only 27%

Answer Posted / jomy peter thomas

homology modeling is actually comparitive modeling.
so threading is the best option..

Is This Answer Correct ?    2 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?

1702


What are oesophageal molecular markers?

1684


Will the plant able to produce electricity when the soil is dried up

1200


How do you customize database for blast?

611


What is the criteria for LTQ (LC-MS/MS) SEQUEST search?

1932






How a cluster algorithm works?

1592


What is the science of bioinformatics?

616


Can independent origins be established for two families of transport systems having no sequence or motif similarities without three-dimensional structural data?

594


What is C-compliator?

1828


What is enzyme-ligand interaction?

1540


What are the bioinformatic tools applied to micromolecular evolution?

587


Have the proteins of a family generally acquired distinctive properties within each of these three kingdoms for ancient families that arose before bacteria, archaea and eukaryotes diverged?

626


How do you find the most recent human sequence data in the data bases inorder to determine physical maps?

1611


What do you think are the more interesting areas of bioinformatics?

634


Suppose the Blast search returned 100 hits. Of these, 17 were false positives and we knew that there were 165 sequences in the database which should have returned a hit with our sequence. How many false negatives were there, and what is the sensitivity and selectivity of Blast in this instance?

1850