what is the difference between M.C and LOD
Answers were Sorted based on User's Feedback
Answer / ankalreddymsc
BY m.c WE CAN FINDOUT ONLY WATER CONTENT IN A DRUG
While trrough lod we can also know about non volatile
solvents present in a drug.
Is This Answer Correct ? | 105 Yes | 25 No |
Answer / alpesh patel
M.C. result gives only water content present in substance
while LOD result gives water content+solvent present in
substance. Thus, LOD content is always hIgher than M.C.
Is This Answer Correct ? | 91 Yes | 19 No |
Answer / i.kizar ahamed
MC gives only % of water in a substance(Low melting range
substance).But LOD result is a combination of water
content and other volatile organic solvents.And more over
Melting range of a substance has to be considered in case
of LOD. Substances whichever is having high melting point
is required for LOD checking.
Is This Answer Correct ? | 56 Yes | 7 No |
Answer / amit patel
M.C =moisture content= the molecular water stored in the
molecule/it gives the exact water centent.(generally tested
by the KF titrator)
whereas
LOD=Loss on drying= unbound water + organic volatile
impurities.(in vacuum oven)
Is This Answer Correct ? | 34 Yes | 3 No |
Answer / minal
Moisture content gives value of bound and unbound water
content while LOD gives value of unbound water plus non
volatile solvent content
Is This Answer Correct ? | 25 Yes | 5 No |
Answer / s. jayapal reddy
M.C BY K.F:GIVES THE INFORMATION ABOUT INTRAMOLECULAR AND
EXTRAMOLECULAR WATER CONTENT OF THE MOLECULE.
L.O.D: GIVE THE INFORMATION ABOUT ORGANIC SOLVENTS AND
EXTRAMOLECULAR WATER CONTENT IN THE MOLECULE
Is This Answer Correct ? | 15 Yes | 1 No |
Moisture content means how much water present in your
product or test sample
LOD Means how much non volatile solvents + water present
in your product or test sample
Is This Answer Correct ? | 15 Yes | 5 No |
Answer / ss
Moisture content means how much water present in your
product or test sample
LOD Means how much volatile solvents + water present
in your product or test sample
Is This Answer Correct ? | 10 Yes | 1 No |
Answer / swarupa kumar behera
M/c (moisture content) - It determine that how many quantity of water present in supplied sample. It generally check by Karlfisher.
LOD ( lose on Drying)- determine both water and non-volatile substance in supplied sample. It done in oven at 110'C for 1hr.
Is This Answer Correct ? | 9 Yes | 2 No |
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