Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 55751

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 6495

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2073

why using buffers in hplc inteed of water

5 12182

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 2436

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 4756

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 5546

In specificity what parametrs are consider why that parametrs

2 5794

ash or residue in that what will be there.

3 5220

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 2646

What is difference between oos

Gennex,

7 25865

what is the differance between Analytical and semi micro balance?

2 12552

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10077

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 6242

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 13069


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Un-Answered Questions { Analytical Chemistry }

What is delay volume?

842


What are modes of quantification in related substances

1716


what is mean by dissolution hydrodynamics?

342


why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?

2335


Why perchloric acid used for potentiometric titration

2152






could negative ions be produced by bombardment process in mass spectrometry?

1284


which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

1721


What is the difference between chromatographic purity and related substances?

778


Related substance method equivalency on control sample or spiked sample?

297


How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2009


Why dissolution test is not performed in all of the products

2025


What is third generation HPLC Columns?

1503


How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

2858


Why we used in n-butyl acetate water content terminology while in ethyl acetate we used moisture content terminology?

1370


EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE

2124