before starting analytical method valodation what you checking? and how giving preference to start validation?
814effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?
936Post New Analytical Chemistry Questions
how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.
how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,
What is dose dumping? why require to do?
Why we check moisture,ash & AIA in product
how require to set assay concentration for standard and sample?
What is viod volume and peak purity in HPLC?
Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
if content uniformity passing but dissolution varrying then what is next step?
how can I make the copper get white bye any salt or acit?
what is mean by covalidation
from where i get mortar pastle for glass bottle crush? it's required for testing of it?
Why a1% value is used for some product ? What is the criteria for selection a1% value ?
How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.
What is stray light in uv what are units for stray light