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What is the difference between the passage number of a cell
line and its population doubling level?



What is the difference between the passage number of a cell line and its population doubling level..

Answer / guest

The passage number simply refers to the number of times the
cells in the culture have been subcultured, often without
consideration of the inoculation densities or recoveries
involved. The population doubling level refers to the total
number of times the cells in the population have doubled
since their primary isolation in vitro.

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