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Cystic fibrosis (CF) occurs with a frequency of about
1/2500 Caucasian newborns and is inherited as an autosomal
recessive. A woman had an older sister die from
complications of this disease. CF is not present among
relatives of her husband. Both the woman and her husband
have normal phenotypes. What is the chance this couple will
have a CF child?
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Answer / Krish
The chance this couple will have a CF child is 1/4 or 25%.
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