On what basis Friability limit NMT 1.0%w/w is recommended. what is impact on formulation if this limit exceeds.
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Answer / Anurag Lohant
The friability limit of 1.0%w/w (by weight) is recommended in pharmaceutical and related industries to ensure the uniformity, strength, and consistency of tablets or capsules. Exceeding this limit may lead to an increase in dust during manufacturing, making it difficult to maintain the desired dose consistency and causing poor quality control issues.
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