explain henderson-hasselbalch equation?
Answer / biomaster
The quantitative relationship among PH,buffering action of
amixture of weak acid and its conjugate base and the PKa of
the weak acid is given by a simple expression called
HENDERON-HASSELBALCH EQUATION.
The shape of titration curve of any weak acid is expressed
by Henderson-Hasselbalch equation.This is auseful way of
restating the expression for the dessociation constant of
an acid.
For the dessociation of aweak acid HA into H+ and A-,this
equation can be derived as follows.
Ka=[H+][A-]/[HA]
by rearraning the equation for solving H+
[H+]=Ka[HA]/[A-]
by converting to logarthmic functions
log [H+]=LOG Ka+log[HA]/[A-]
making expression negative
-log[H+]=-logKa-log[HA]/[A-]
SUBSTITUTING ph for -log[H=] and PKa for -logKa
PH=PKa-log[HA]/[A-]
NOW TO REMOVE MINUS SIGN INVERT LAST TERM I.E -LOG[HA]/[A-]
TO OBTAINHENDERSON-HASSELBALCH EQUATION.
PH=PKa-LOG[A-]/[HA];
Is This Answer Correct ? | 5 Yes | 0 No |
what is Alzheimer's disease?what are its symptoms?
To what organic group do pentoses belong?
What is Ampholyte?
What is the product formed when aminoacid reacts with benzaldehyde?
WHAT IS POLENSKE NUMBER?
1 Answers Biological.e.limited,
An unusual structure is formed at the 5? end of each cellular mRNA. What is it? After this has formed, does the mRNA have a 5? terminus? Explain.
1 Answers Pace Pharmaceuticals,
How are reaction rates dependent upon free energy changes?
According to the watson – crick model how many polynucleotide chains does a dna molecule has?
how much the size of nitrocellulose membrane should be in southern blotting.
What is the other name of sulphur?
what are anaplerotic pathways?
Define limiting radius?