Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the diference between residual solvents and organic volatile matter

RA Chem Pharma,

1475

WHY given much noise PDA dector then VWD Dector

1491

How to decide the standard concentration for related substances hplc method

1 3561

Why we have to use KBr pellet technology ?

1 2556

Why dissolution test performed on six jar?

Mylan,

1 3432

How to determine retention time in Chromatography

Mylan,

2 5033

effect of Ph during analytical run ?

Lambda Therapeutic Research,

1 2336

USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

Srini Pharmaceuticals,

1546

is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

Aarti Drugs,

1652

Which is the highly polar and highly non polar column in HPLC?

1767

What is the difference between qualitative and quantitative analysis (hplc)

1 3794

what is the difference between potentiometric titration and karl fischer titration?

2405

How NMR spectra can be calibrated in presence or absence of TMS?

1 2101

What is Band broading effect explain

Dr Reddys,

1387

we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

Cipla,

1350


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Un-Answered Questions { Analytical Chemistry }

what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?

9421


what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1483


what is partion and column chromatography

1808


Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

1454


WHY pKa value is more important than pH value of the mobile phase in HPLC?

1248






How can we calculate offset value pH measurment

1061


please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1092


which batch require to use for analytical method validation?

324


function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

2055


what is the difference between potentiometric titration and karl fischer titration?

2405


What is split ratio in Gc? Splitless? how requirr to select?

315


identification is for unknown? qualification for known? reporting for LOQ?

272


I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

2962


on the basis of bcs class how to proceed the solubility?

269


what is definition of validation? which components are followed give detail?

1823