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USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
2015is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth
2173we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
1872Post New Analytical Chemistry Questions
what is mean by covalidation
What is the diference between residual solvents and organic volatile matter
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
why we use a particular hplc column for a particular compound give reasons?please
What is the use of tlc and hplc? And when and where use?
How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium
What is column in chromatography?
What is a difference between potency and purity?
How we can identify process related and degradation impurity in single method with short period?
why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space
Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards
what is diffrence between specificity and selecivity?
