Genetics Interview Questions
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In humans, freckles are dominant to no freckles. A man with freckles is married to a woman with freckles, but the children have no freckles. What's the reason?

2 9682

In horses, B = black, b = brown, T = trotter, t = pacer. A black pacer mated to a brown trotter produces a black trotter offspring year after year. What are the probable genotypes?

1 3950

In human beings, brown eyes are usually dominant over blue eyes. Suppose a blue-eyed man marries a brown-eyed woman whose father was blue-eyed. What proportion of their children would you predict to have blue eyes?

1 15917




A brown-eyed man whose father was brown-eyed and whose mother was blue-eyed married a blue-eyed woman whose mother and father were both brown-eyed. The couple has a blue-eyed son. What are the genotypes of all individuals?

1 6990

In hogs a gene that produces a white belt around the animal's body is dominant over its allele for a uniform body. Another independent dominant gene produces fusion of the hoof (syndactyly). Suppose a uniformly colored hog homozygous for syndactyly is mated with a normal footed hog homozygous for the belted character. What would be the phenotype of the F1? If the F1's interbreed, what would be the phenotypic ratio of the F2?

3629

For each of the following, state whether it is a gamete or a genotype of an individual a) TT b) Tg c) IcCC d) TW

2 2226

The gene for tallness (T) is dominant over the gene for shortness (t) in pea plants. A homozygous dominant pea plant is crossed with a heterozygous pea plant, and 200 seeds are produced. Approximately how many of these seeds can be expected to produce plants that are homozygous dominant?

3 7695

People who can roll their tongues contain a dominant allele for tongue rolling. If people do not contain the tongue rolling gene, then they cannot roll their tongue no matter how hard they try. Consider the following situation: If a homozygous dominant tongue roller mates with a homozygous recessive non-tongue roller, then what is the probability of the offspring inheriting the tongue rolling gene?

2 8222




Why are some people born with Rh-positive blood while others are born with Rh-negative blood

1 2564

What is Genetic Engineering?

1 872

What are the differences between Genetic Engineering and breeding?

1 1625

Does Genetic Engineering harm or benefit human society?

1 5685

What are the down sides of Genetic Engineering?

885

Can you name a few potential risks of Genetic Engineering?

921

How is Genetic Engineering currently used?

1349


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Un-Answered Questions { Genetics }

How will you differentiate alleles of a gene in the double strand of DNA?

1128


The ABO blood system has been employed to settle cases of disputed paternity. Suppose, as an expert in genetics, you are called to testify in a case where the mother is type A, the child is type O and the alleged father is type B. How would you respond to the following statements of the attornies: a. "Since the mother has type A, the type O of the child must have come from the father and since my client is type B, he obviously could not have fatered the child." Made by the attorney of the alleged father. b. "Further tests revealed that this man is heterozygous and therefore he must be the father." Made by the mother's attorney.

1156


Does unwinding DNA cause aging?

992


A single base exchange mutation occurs in the promoter of the TRP operon. How the operation of the HIS operon might be affected in two ways?

1143


A blastomere was removed from an 8-cell human embryo, and its beta-globin gene was amplified by PCR. The beta-globin DNA was treated with an enzyme that cuts on either side of and within the normal allele (producing a small fragment), but not within the sickle cell allele (producing a large fragment). Electrophoresis of the treated DNA from the blastomere demonstrated the presence of both a large and small fragment derived from the beta-globin genes. How should you interpret this test?

867






What situations might be viewed as ethical uses of human cloning? Are you doubtful, fearful, or hopeful about human cloning?

1138


Is Jurassic Park -- Completely impossible?

1069


In mice colored coat is dominant to albinism. Sniffles, a male mouse with a colored coat is mated to Esmeralda, an alluring albino. The resulting litter of six young all had colored fur. The next time around Esmeralda was mated with Whiskers, who was the same color as Sniffles; some of this litter were white. a)What are the probable genotypes of Sniffles, Esmeralda, and Whiskers? b) If a male of the 1st litterwas mated to a colored female of the 2nd litter, what phenotypic ratio might be expected among the offspring? c)What would be the expected results if a male of the 1st litter was mated to an albino from the 2nd?

1818


The village of Oblong has 400 normally-shaped residents. Transferrin is an iron carrier found in blood, and electrophoretic variation of this protein is determined by an autosomal codominant system. The citizens of Oblong were typed for their transferrin complements. The distribution of transferrin phenotypes was: 100 CC, 100 CD, and 200 DD. What is the frequency of the C allele?

832


Cystic fibrosis (CF) occurs with a frequency of about 1/2500 Caucasian newborns and is inherited as an autosomal recessive. A woman had an older sister die from complications of this disease. CF is not present among relatives of her husband. Both the woman and her husband have normal phenotypes. What is the chance this couple will have a CF child

923


how to Create population with sufficient genetic diversity ?

1054


Differentiate between biotechnology and bioengineering?

1233


7) Diabetes is recessive. A) If woman has diabetes and marries a man that doesn’t have it, is it possible for their offspring to acquire this disease? A A Aa Aa Aa Aa a a genotypes Phenotype 100% Aa, Heterozygous 100% No diabetes B) If none of the father’s ancestors had ever had diabetes, would their children have a chage of getting the disease? Explain

685


what happens in Postmeiotic segregation?

1208


what is the role of Beta-lactamase in Gene Cloning ?

1102