signifcance of detector lenearity in calibration f hplc
Answers were Sorted based on User's Feedback
Answer / mr.bujji reddy kanchi
The detector is giving Linear results means the areas of an
injection of specific concentration are relative.
that menas
if the concentration of the sample X is 0.1 %, imagine the
area is 1000.
if the concentration of X is doubled 0.2%, the area will
also be doubled that is 2000.
This relation ship is called linearity.
If the detector gives linear responses with respect to
concentrations. then the instrument works properly . then
it is calibrated.
| Is This Answer Correct ? | 17 Yes | 0 No |
Answer / chandu 4m apex
y v r doing linearity means to check the accurate response of detector, if u increase con gradually.
| Is This Answer Correct ? | 0 Yes | 0 No |
why we are using 6 dosage units in dissolution, and why we are using 6 tablets in disintegation test.is there any scientific reason beyond 6?
How to establish relative response factor for hplc. Why it is required?
In chromatograpbic purity 90% is there, in assay 70% is there. How will you prove remaining 30%.
What is the meaning of 624 in DB-624 Capillary column used in GC?
What is the SOP for SOP
In pharmacopeal solibility parameter of a material, is et essential to test all paramete? If 70-75% parameter passes can we assess that the material is satisfactory or not?
why 6 tablets use for dissolution
1 Answers Cadila, IPCA, SUN, Teva Pharmaceuticals,
What is the principle of hplc detectors like.. UV detector,flurosence detector, RID?
Why Urasil and Caffeine use for HPLC wavelength accuracy calibration. which is most suitable, Why? other than these which can be used?
In UV calibration we use Holmium perchlorate solution made in 1.4M perchloric acid The question is that 1.4 M perchloric acid we make is it in water or glacial acetic acid?
Why we use 100 RPM in friability test
On which pharmacopoeia basis we can calibrate instruments like HPLC,GC,UV,DISSO,IR etc...
9 Answers Cipla, Laurus, Micro Labs,