In dissolution test s1 stage we are getting one bowl 40 % out of 6 bowls what is the root cause you find and how proceed next step? ( Q is 80%)
3 4651what is the effect of injection volume calculate flow rate in perkin elmer headspace? (ccm parameter in HS)
1 3085How can we calculates the solubility of the drug in different medias by injecting in to hplc????(solubility studies)
2 4920In chromatograpbic purity 90% is there, in assay 70% is there. How will you prove remaining 30%.
3 8618Post New Analytical Chemistry Questions
What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?
1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer
Why we use potassium dichromate in uv calibration Exact reason behind it??
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?
What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?
if peak get problamatic then what require to do?
Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc
How to determine water content of bis tetrazole amine mono ammonium salt
how require to fix the linearity and accuracy cincentration range?
which are the diffrent batches in the pharmaceuticals?
how to qualify the impurity?
[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?
how to calibrate hplc & gc
If vendor having more imp than monograph then how to proceed? and how to set spec?