balaram


{ City }
< Country > india
* Profession * chamist
User No # 87097
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Total Answers Posted # 14

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Questions / { balaram }
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Answers / { balaram }

Question { Vimta Labs, 12242 }

What is the purpose & importance of using the
polystyrene film in ir calibration?


Answer

POLYSTARENE FILM MADE BY POLYMER OF STYRENE. IT IS HIGHLY
DURABILITY AT ANY TEMPARECTURE.
POLYSTARENE FILM GIVES SHARP PEAKS WHICH COVER WHOLE IR
RESION.

Is This Answer Correct ?    9 Yes 3 No

Question { Graviti Pharmaceuticals, 8361 }

what is Fourier Transform


Answer

IN IR LIGHT THROUGH THE ANALYTE SOLUTE BASED ON CHANGES IN
VIBRATIANOL ROTACTIONAL MOMENTS OF THE ATOMS PRESENT IN THE
MOLUCULE WHE CAN IDENTIFIED THE FUNCTIONAL GROUPS IN THE
SAMPLE

Is This Answer Correct ?    3 Yes 0 No


Question { 7122 }

what are the role of MR


Answer

MR MEANING IG MELTING RANGE.
SO IDENTIFIED MELTING POINT IS SAMPLE.

Is This Answer Correct ?    3 Yes 2 No

Question { 12175 }

why using buffers in hplc inteed of water


Answer

BUFFERS IS USED TO DEPAND UP ON THE DRUG PKa VALUES
BUFFERS PH IS ALLWAYS (+) OR (-)1
BECAUSE IS USED PHASPATE OR ACETATE BUFFERS IS USED

Is This Answer Correct ?    1 Yes 2 No

Question { 10260 }

I got 88.0 % assay for a drug in HPLC analysis for same
injection i got 40.0% related substances is it possible?
what is the relation between results of assay and purity?


Answer

PURITY IS QUALITATIVE ANALASIS
BUT ASAAY IS QUANTITATIVE ANALASIS.

EXP:-
CIPROFLOXACINE EXP
THIS PRODUCT PURITY IS 99.5% BUT ASSAY IS 99.8%
THE SAME PRODUCT PURITY IS 99.5% BUT ASSAY IS 80.0%
THE SAME PRODUCT PURITY IS 99.5% BUT ASSAY IS 50.0%
BECOUSE PURITY IS NOT DEPEND UP ON THE ASSAY.

Is This Answer Correct ?    11 Yes 1 No

Question { Rakshit Drugs, 17191 }

why we use polystyrene film for ftir calibration?


Answer

polystyrene film made by polymer of styrene,
it is highly durability.


polystyrene film is all bands executed which cover whole IR
Region.

Is This Answer Correct ?    7 Yes 2 No

Question { MSN Pharma, 31716 }

In case of HPLC coloums what is the difference Between C8 &
C18 coloums & how can we select difference type of coloums
like Inertial ODS , Hypersil BDS , ODS etc.?


Answer

HPLC in mainly two types of columns is used
These are (1)Normal phase columns
(2)Reverse phase columns

C18 And C8 COLUMNS both are reverse phase columns.
C18 columns is highly polar columns compare with C8 columns

C18 Column Structure is OH-Si-C18 linkage

C8 Column Structure is OH-Si-C8 linkage

These columns is depend up on the compound natchere

ODS means OCTA DECYLE SILANE. This types of columns
is used mainly acidic nacture compounds.

BDS means BASE DEACTIVATED SILANE. This types of columns
is used mainly basic nacture compounds.

Is This Answer Correct ?    19 Yes 10 No

Question { Hapten Healthcare, 31331 }

Why triethylamine and o-phosphoric acid used while setting
pH of mobile phase during HPLC Analysis?


Answer

TRI ETHYLAMIINE (AND) ORTHO-PHOSPARIC ACID ARE
USED pH ADJUSTMENT PERPASE

BECOSE
1)GOOD RESOLUTION
2)PEEK SHAPE

Is This Answer Correct ?    12 Yes 3 No

Question { Cipla, 9894 }

for which type of applications gas chromatography is used?


Answer

MAINLY GC IN USED THERMALLY STABLE COMPOUNDS (NON VOLATILE
COMPOUNDS)

MAINLY GC TEST TO IDENTIFIED ORGANIC SOLVENTS

Is This Answer Correct ?    0 Yes 12 No

Question { 7854 }

wat is reverse phase in hplc


Answer

MAINLY TWO TYPES IS USED
THESE ARE (1)NORMAL PHASE
(2)REVERSE PHASE

1)NORMAL PHASE:-POLAR STATIONARY PHASE
NON POLAR MOBILE PHASE

2)REVERSE PHASE:-NON POLAR STATIONARY PHASE
POLAR MOBILE PHASE

Is This Answer Correct ?    9 Yes 2 No

Question { Claris Lifesciences, 12490 }

why water factor is near about 5.0 in kf titration?


Answer

1 ml of kf Reagent is neutralized 5 ml of water Becose KF Factor is around 5

Is This Answer Correct ?    7 Yes 15 No

Question { Glenmark, 27818 }

Which column is more polar, C8 or C18?


Answer

C18 columns is more polar

Is This Answer Correct ?    9 Yes 55 No

Question { MSN Pharma, 18620 }

Retention time & Relative Retention time Definition &
between difference?
How to Calculate response factor(RF) & relative response
factor(RRF)?


Answer

Rt is identified main peak.
but rrt is identified impurities purpose

rt*rrt-impurities rt is identified

Is This Answer Correct ?    11 Yes 3 No

Question { MSN Pharma, 9935 }

why are using toluene in uv calibraion in resolution
performance


Answer

Toluene is given minimum and maximum absorbance in nearest nanometer. Because use toluene.

Is This Answer Correct ?    19 Yes 1 No