How to stop proliferation?
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Answer / Manoj Kumar Singh
To stop cell proliferation, several strategies can be employed: 1. Serum starvation: Removing growth factors (such as serum) from the culture medium can induce cell cycle arrest in certain phases. 2. Use of inhibitors: Certain drugs, such as mitomycin C and aphidicolin, can block specific steps in the cell cycle. 3. Induction of differentiation: For some cell types, inducing differentiation can lead to growth arrest, as differentiated cells often lose their ability to proliferate.
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