What are Beta-lactams?

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What are Beta-lactams?..

Answer / guest

A beta-lactam ring (β-lactam) or penam is a lactam with a
heteroatomic ring structure, consisting of three carbon
atoms and one nitrogen atomA beta-lactam ring (β-lactam) or
penam is a lactam with a heteroatomic ring structure,
consisting of three carbon atoms and one nitrogen atomA
beta-lactam ring (β-lactam) or penam is a lactam with a
heteroatomic ring structure, consisting of three carbon
atoms and one nitrogen atom

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What are Beta-lactams?..

Answer / rajasekhar

These are crucial enzymes in the cross-linking of
peptidoglycan .

The basic building block of the cell wall
act as a false substrate for D-alanyl-D-alanyl
transpeptidases requires carboxylate or sulfonate group of
beta-lactam to react the a serine residue of
transpeptidases to give an inactive acylated enzyme
transpeptidases are located in periplasmic space.

They are capable of hydrolysing penicillins, broad-spectrum
cephalosporins and monobactams. Often associated with
resistance to aminoglycosides and fluoroquinolones .

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