Bio Informatics Interview Questions
Questions Answers Views Company eMail

How to run DOCK 6 using cygwin?

1 5808

What are the main signals used for gene finding in prokaryotic genomes? How are these signals introduced into the search algorithms?

1 2829

What are the main approaches of predicting protein interactions using genomic context analysis?

1 3023

What is the main idea of maximum parsimony in phylogenetic tree construction? What are the drawbacks?

2 4983

Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?

1696

Which of the following sequences contains the pattern [AG]-x (4)-G-K-[ST] from the PROSITE database? seq. A: VAGWGKST seq B: GVLKRGKS seq. C: AGVLKGRT seq. D: AGVGKSTP

5 6033

If a match from a sequence database search is reported to have an E-value of 0.0, should it be considered highly insignificant or highly significant?

3 4643

Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ user sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?

Infosys,

4 6556

How you caluculate sensitivity and selectivity of Blast?

2 7389

which instrument is most commonly used to observe the external features of grasshopper's abdomen?

1 9016

How can i do the Homology Modeling of GPCR receptor successfully? My target identity with template is only 27%

4 4577

what is the length of the exon and intron

3 6152

what is e value?

4 9191

What are the responsible factors for extinction of flora and fauna ?

CAT,

3 11399

How is the respiratory system applied to the sport paintball?

1 3610


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Un-Answered Questions { Bio Informatics }

Did bacteria, archaea, and eukaryotes exchange transporter genes appreciably during the past two billion years?

654


How to Count number of nucleotide substitutions ?

1781


What are the main differences between parsimony,distance and likelihood-based algorithms?

1675


How long will a train 100m long traveling at 72kmph take to overtake another train 200m long traveling at 54kmph?

2898


How to caculate coordinates of each atoms on 3 D HP model?

1682






What is the secondary structure of intron ?

1659


Did integral membrane transport proteins arise as an independent protein class or from other types of proteins?

541


What are the bioinformatic tools applied to micromolecular evolution?

578


What is the idea behind ?weighting? sequences in the package CLUSTAL W for multiple alignment? How are these weights calculated?

1533


Have the proteins of a family generally acquired distinctive properties within each of these three kingdoms for ancient families that arose before bacteria, archaea and eukaryotes diverged?

616


Does multidrug resistance (mdr) arise by activation of stable genes encoding drug efflux pumps or by mutations of genes encoding other types of transporters in bacterial pathogens?

639


How to find flanking region ?

1954


How the Algorithm works?

1516


What is protein sequencing?

648


Why do you think that bioinformatics is important?

605