What are the main signals used for gene finding in prokaryotic genomes? How are these signals introduced into the search algorithms?
1 2829What are the main approaches of predicting protein interactions using genomic context analysis?
1 3023What is the main idea of maximum parsimony in phylogenetic tree construction? What are the drawbacks?
2 4983Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?
1696Which of the following sequences contains the pattern [AG]-x (4)-G-K-[ST] from the PROSITE database? seq. A: VAGWGKST seq B: GVLKRGKS seq. C: AGVLKGRT seq. D: AGVGKSTP
5 6033If a match from a sequence database search is reported to have an E-value of 0.0, should it be considered highly insignificant or highly significant?
3 4643Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ user sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?
4 6556which instrument is most commonly used to observe the external features of grasshopper's abdomen?
1 9016How can i do the Homology Modeling of GPCR receptor successfully? My target identity with template is only 27%
4 4577Post New Bio Informatics Questions
Did bacteria, archaea, and eukaryotes exchange transporter genes appreciably during the past two billion years?
How to Count number of nucleotide substitutions ?
What are the main differences between parsimony,distance and likelihood-based algorithms?
How long will a train 100m long traveling at 72kmph take to overtake another train 200m long traveling at 54kmph?
How to caculate coordinates of each atoms on 3 D HP model?
What is the secondary structure of intron ?
Did integral membrane transport proteins arise as an independent protein class or from other types of proteins?
What are the bioinformatic tools applied to micromolecular evolution?
What is the idea behind ?weighting? sequences in the package CLUSTAL W for multiple alignment? How are these weights calculated?
Have the proteins of a family generally acquired distinctive properties within each of these three kingdoms for ancient families that arose before bacteria, archaea and eukaryotes diverged?
Does multidrug resistance (mdr) arise by activation of stable genes encoding drug efflux pumps or by mutations of genes encoding other types of transporters in bacterial pathogens?
How to find flanking region ?
How the Algorithm works?
What is protein sequencing?
Why do you think that bioinformatics is important?