What is difference between Base and Nucleophile?
Answers were Sorted based on User's Feedback
*There are much more similarities between base and
nucleophile.Base attacks at more acidic protons while
nucleophile attaks at electron deficient carbon.
e.g. LDA--- Base
OH- Nucleophile as well as a base.
Nucleophile may also act as a base.
Is This Answer Correct ? | 76 Yes | 16 No |
Bases attack at more acidic protons while Nucleophiles
attack at electron deficient atoms.
Generally, stronger base acts as weaker nucleophile and
weaker base acts as strong nucleophile.
e.g.
LDA is strong base as well as weak nucleophile.
Is This Answer Correct ? | 45 Yes | 9 No |
Answer / srinivas
All nuecleophiles can act as base but all bases can not
act as nucleophiles
Is This Answer Correct ? | 35 Yes | 14 No |
Base is a specie that donates an electron pair or extracts a proton from other molecule. A neucleophile is a specie that attack on positive or electron deficient site. Both base and neucleophile have excess of electrons. They may be negatively charged, neutral or partial negative portion of a polar molecule. The main difference between them is that a base extract H from other molecule and neucleophile attaches to the molecule itself. It should be moved that a strong neucleophile is a weak base and vice versa e.g. Chloride is a strong neucleophile due to its small size and electronegative nature but it is a weak base because it does not give electron pair easily (outermost electrons are tightly bound due to small size). Similarly, Iodide is a strong base but weak neucleophile due to large size.
Is This Answer Correct ? | 25 Yes | 6 No |
Answer / manoharan r
In bases the deriving force is only electron donation but
in nucleophiles a new bond should be formed.For example
hindered bases are week nucleophiles.
Is This Answer Correct ? | 14 Yes | 6 No |
Answer / yogesh
There are much more similarities between base and
nucleophile.Base attacks at more acidic protons while
nucleophile attaks at electron deficient carbon.
e.g. LDA--- Base
OH- Nucleophile as well as a base.
Nucleophile may also act as a base but at some conditions.
Bases attack at more acidic protons while Nucleophiles
attack at electron deficient atoms.
Generally, stronger base acts as weaker nucleophile and
weaker base acts as strong nucleophile.
eg
aq. KOH acts as base
and alco. KOH act as nucleophile
Is This Answer Correct ? | 12 Yes | 7 No |
Answer / easha
base attacks on proton and nucleophiles attack on electroic
carbon. but i don't understand how many bases and
nucleophiles are different from each other?
Is This Answer Correct ? | 7 Yes | 6 No |
Answer / prashant shinde
Base abstract the electron pair to carbon atom. and nucleophile donate the electron pair to carbon atom.
Is This Answer Correct ? | 2 Yes | 2 No |
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