what is end capping in hplc coulmn
- 2 Answers
- 11775 Views
- Lupin, Zydus Cadila, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / kiran ambekar
Capping of exposed silanol with short chain HC chain
ie.Trimethyl chlorosilane.
Now a day all columns are end capping.
generally End capping column is used for basic compounds
for reducing the peak tailing
| Is This Answer Correct ? | 23 Yes | 3 No |
Answer / r.kadambavadani
In chromatography, endcapping refers to the replacement of accessible silanol groups in a bonded stationary phase by trimethylsilyl groups.
Endcapping technology prevents the tailing of a polar compound's peak and shows very high durability even with an alkaline mobile phase because of the strong film covering the stationary phase surface.
| Is This Answer Correct ? | 1 Yes | 0 No |
what is procedure of actual procedure for registration of drug?
mixed 1.0 ml of methanol and 1.0 ml of toluene and injected in gas chromatography.will you prove that both solvents are in the ratio 1:1(not by area normalization)
what is the balance drift?
why a ph meter require KCL solution for their storing condition?
In standard weight box used for calibration of analytical balance there are two numbers (Qty) of 20mg, 200mg,2.oGM weights. Why?
why we are used 4,7,9,2 buffers for the ph calibration
4 Answers Aurobindo, Enaltec Labs,
What is Standard deviation
how PH an important role in HPLC separation
why we are adjusting the ph in buffer solution preparation
Why we are using only KBr in IR spectrometer why not KCl
Why we use 100 RPM in friability test
What is Fourier Transform Spectrosopy?
5 Answers Aurobindo, Hetero, Lupin,
Organic Chemistry 
