why are not used methonol in kf titrator to find out water
content in ketones?
Answers were Sorted based on User's Feedback
aldehydes and
ketones,
interfere with
the
normal Karl
Fischer
titration as
they react with
methanol to form
water which is
also titrated.
The
Karl Fischer
titration shows
an
incorrect, too
high water
content
or vanishing end
points with
classical
reagents
Is This Answer Correct ? | 13 Yes | 0 No |
Answer / madhukar tayade
Aldehyde and ketones are react with the methanol to form the Ketal formation so that aldehyde and ketone cant give the moisture in methanolic medium.
Is This Answer Correct ? | 5 Yes | 0 No |
Answer / jagadeeshchandra
Generally methanol is not used as a solvent for carbonyl
compounds.Usage of methanol for ketones will produce ketals
and water which gives false result.And aldehydes gives acetals
and water.
pyridine can be used in place of methanol.Halogenated
alcohols,long chain alcohols,Dimethyl formamide can also be
used.
Another thing methanol is reaction part.It forms methyl
sulphite with kf reagent.Whare base will acts as a buffering
agent.
More information i can give.If intrested call me
9989936333
Is This Answer Correct ? | 5 Yes | 0 No |
Answer / padmarao
methonl is reacts with ketones to form water so wecare used to
pyridine as a solvent
Is This Answer Correct ? | 3 Yes | 1 No |
methanol react with ketones and forms ketoxals + water.
so we will get more % of water content which is present in
compound
Is This Answer Correct ? | 2 Yes | 0 No |
in hplc chromatogram started from left to right and in uv spectrum started from left to right
why we want incorporate area of each solution of Intermediate precision and repeatability as well as Accuracy ? What is the use to incorporate area of each solution of Intermediate precision and repeatability as well as Accuracy ?
wat is reverse phase in hplc
What is dose dumping? why require to do?
why we need to do karl ficher fector ?
What is the role of SO2,I2, Methanolic hydroxide and any base in Karlficher titration
2 Answers Medley Pharmaceuticals,
what is the most common FT-IR source used for the MID&Near IR regions?
1 Answers Dr Reddys, Piramal Enterprises,
why we use kbr as constant in the FTIR ?
Why we are having specification 100% above in case of assay as there is only 100% of compound?
2 Answers MSN Pharma, Nectar Lifesciences,
hi i am m.sc organic chem and complete analytical lab tech dipolma now job in qc many time ask question you in m.sc organic why job in qc please help me i can not give proper ans please tell me
3 Answers Arch Pharmalabs, Natco,
Many times I don't got a caffeine peak in calibration of hplc using guard column ❓
for heavy metal test lead used in which form pure form or any other form for preparation of lead standard sol
1 Answers Watson Pharmaceuticals,