What is the Deference between Bulk density & Tap density ?
- 2 Answers
- 23979 Views
- Hikma Pharmaceuticals, Neuland, Reddy Labs, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Untapped Density = bulk density
Bulk density is the simply fill capacity of any vessels.
we take a 100ml cylinder and fill it with any
substance(Approx-x gram) and read the volume of cylinder.
then the bulk density= weight of substance/ml of cylinder.
unit = gm/ml or gm/cc
but the tapped density is that density which measure after
tapping according to monograph (USP-1, USP-2)we use it when
ever the volume of substance not to be constant.
(for USP- 1 it should be 350 stocks. and for USP -2 it
should be 250 stocks.which we use in calibration of Tap
density tester.)
| Is This Answer Correct ? | 28 Yes | 1 No |
Bulk Density (0 taps or Untapped): As is volume in
g/ml.This is called as apparent volume.
Tapped Density: after tapping only we can measure the qty
as g/ml. As per USP two types of methods is there, Method-
I&II.
Based on the powder nature tapping are fixed.500 taps, 750
taps & 1250 taps.(Varience% is NMT 2%)
Naturally all powder grades are fixed in 1250 taps.
After 1250taps also varience is more, then go to USP-II
method or any customer requirement is there then we can use
Method-II.
| Is This Answer Correct ? | 18 Yes | 2 No |
In partical size by malven,which parameter is generlly change for development of dry and wet method.
why 2Theta value is consider in the XRPD spectra and how to consider the 2 Theta value
What is similarity factor?
in gas chromatography what is the difference between gas flow rate and average linear velocity ?
If vendor having more imp than monograph then how to proceed? and how to set spec?
In the gas chromatography what is used carrier gas and make up gas?
wat is the role of michelson interferometer in FTIR and He-Ne lase.detailed answer required in simple language
in dissolution why pool sample needed? in which type of drug pool sample need?
During Validation study, Recovery is passing at all levels but Linearity is failing. Justify?
1 Answers Mylan, Torrent Pharma,
Which column is more polar, C8 or C18?
6 Answers Cipla, Glenmark, Laurus, Torrent Power,
Can we do the MC analysis of a sample which is not completely soluble in the medium choosed.
What is discriminating media? How can u justify/select that which media (pH etc...)is suitable for your dissolution study of your compound?
Organic Chemistry 
