What is Specificity ?
Answers were Sorted based on User's Feedback
Answer / subash
Specificity is the ability to assess unequivocally the
analyte in the presence of components which might be
expected to be present. These might include impurities,
degradants, complex matrices, etc.
Is This Answer Correct ? | 11 Yes | 0 No |
Answer / vidyaevuri
Specificity determines the consider peak is single or it co-
eluting with another peak with same retention time. And
peak purity should be pass for comsider peak.
There is no interference of balnk and placebo peaks with
Active peak and impurity peaks. also
Is This Answer Correct ? | 9 Yes | 0 No |
Answer / phanindra
this parameter is used to check the purity's of sample and impurities which we are used in validation,Retention time identification,check the separation of impurities and also used to calculation of RRT AND RRf's
Is This Answer Correct ? | 6 Yes | 1 No |
Answer / vaishali musale
The specificity of the method was determined by analyzing
standard drug &test samples.the purity of the drug
determined by comparing Three regions i.e. peak start peak
apex & peak end.
Is This Answer Correct ? | 4 Yes | 3 No |
Answer / sham
Specificity is one of the experiment name during method
validation. As the name suggests, this exp is done to find
how specific the method is for the analytes being analysed.
PDA detector is used to ensure the absence of co-elusion
and ultimately the specificity.
Is This Answer Correct ? | 2 Yes | 2 No |
Answer / eswar
If the drug substance not dissolved in dissolution medium,then what we do?
Is This Answer Correct ? | 0 Yes | 0 No |
Answer / srinivasreddy
Specificity determines the consider peak is single or it co-eluting with another peak with same retention time. And
peak purity should be pass for consider peak.
There is no interference of balnk and placebo peaks with
Active peak and impurity peaks. also
Is This Answer Correct ? | 0 Yes | 0 No |
what is the diference between spectroscopy and chromatography
2 Answers Cipla, PharmChem, Reliance,
from compund pka value how to select buffer and column?
2 Answers Emcure, Zydus Cadila,
why PH range 0-14 explain
5 Answers DRL, Reddy Labs, Saint Gobain, Viva,
why we use deturium lamp in uv spctrophotometer other than lamps
why did uyou choose analytical chemistry?
What is boiling point ? & Explain.
What is the diffeence between assay and uniformity of content
What is (Q) point dissolution?
How to calibrate glassware against std calibrated glassware?
why do we use around only 60 mg of K2cr2o7 in the UV calibration -control of absorbance test?
how PH an important role in HPLC separation
Is it necessary to inject three replicate for accuracy in AMV.