Answer / mr.shoukatalli naikwade

API molecule without hydrocloride salts are in the form of
base and it is higly non polar.its solubility in water as
well as in our blood and gastric juices in stomach is very
poor.
Our pH of stomach is arround 2 and gastric acid consisting
mainly of hydrochloric acid 0.5%.

To increase API's solubility of drugs,salt formation plays
important role in dissolution and dis integration of tablet.

for salt formation hydrochloric acid is mostly choosed.

why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?

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process of Diclofenac sodium,IP.

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Suppose we prepared pH buffer solution in lab.and calibrate against NIST solution, and same shall going to used upto 30 days. is it possible to stable pH and apperance ? suggest ?

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Why Na lamp is used in polarimeter?

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How we choose the mobile phase for method development.?

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why hydrogen and zero air used for flame ignition in gc?

1 Answers  

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why we are using hexane in calibration of number of drop per mL

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What is intact assay method development.....?

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what is specificity?

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Why we are using K2Cr2O7 for control of absorbance in UV?

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differnc btw c18 and c-8 column

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in karl fischer reagent which solvent is used for dissolving iodine sulphur dioxide and imidazole

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