Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

Difference between uv detector nd RI DETECTOR? wt s the difference between OVI Solvents nd residual solvents incase of GAS CHROMATOGRAPHY? nd wt s its detection limit?

3 16011

on what basis SOP's can be changed? IF mobile phase ratio is 70:30 to how much % can we change the ratio in HPLC process

Cipla, Ranbaxy,

7 17585

Why caffeine as a reference standard used for calibration of HPLC?

Gangwal Chemicals, Orchid,

11 57903

What is the composition of K.F

IPQA,

6 42468

What should be the precision for HPLC during technology transfer?

3 9854

how do start hplc method development? how much sample required for developing the method development?

BMS, Cipla, Indoco Remedies, Sun Pharma,

3 52823

Wt s the use of linearity in HPLC method validation

4 16564

which pharmacopeoia mentions that caffiene is used as a standard for HPLC calibration? which other standardscan be used for the same?

Hetero, Mylan,

1 9202

Why will a solution of aspirin without acid or basic hydrolysis give yellow colour with a solution of Ferric chloride?

1 5791

Why do we use 0.005M h2so4 solution for preparation of k2cr2o7 solution for UV calibration?

Jubilant, Medreich, Mylan,

3 25336

In HPLC what is Single point threshold, peak purity index and minimum peak purity index? what should be consider for pure peak.

3 32370

why the sucrose used in calibration of polarimeter

Neuland,

5 16566

what r the parts calibrated in gc

ELBS, Reddy Labs,

21 38641

acceptance criteria for ph meter, hplc detector,pump,injector,oven when we calibrate.

3 24915

is there any material other than caffene to calibrate hplc detector

Biocon,

13 30059

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Un-Answered Questions { Analytical Chemistry }

In which situation we require to analytical method validation of excipient?

798

Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

1826

if you have given one product then how you determine the impurity in that?

750

How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

4285

what are the standard methods for HPLC?

2792

How can I develope method of dissolution by HPLC OR UV

2414

inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

718

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3131

What is gelatinization?

1629

what is turbidimetric titration?Give 2 examples.

2679

in sampling of raw material which side is pasted sampled labels

1847

What is column in chromatography?

2250

In which situation we require to prepare the standard solution from sample in Related substance method?

787

How we choose the mobile phase for method development.?

1221

If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

1001

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