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The village of Oblong has 400 normally-shaped residents. Transferrin is an iron carrier found in blood, and electrophoretic variation of this protein is determined by an autosomal codominant system. The citizens of Oblong were typed for their transferrin complements. The distribution of transferrin phenotypes was: 100 CC, 100 CD, and 200 DD. What is the frequency of the C allele?
1993Cystic fibrosis (CF) occurs with a frequency of about 1/2500 Caucasian newborns and is inherited as an autosomal recessive. A woman had an older sister die from complications of this disease. CF is not present among relatives of her husband. Both the woman and her husband have normal phenotypes. What is the chance this couple will have a CF child
2073Promoters of housekeeping genes contain variable numbers of GC boxes, but neither TATA nor CCAAT boxes.Inwhat way these properties of housekeeping promoters are helpful?
2115Suppose you are heterozygous for a mutant beta-thalassemia allele. If the frequency of beta-thalassemia is 1/1600 persons, what is the probabilty that your prospective spouse is heterozygous for a mutant beta-thalassemia allele?
2071The village of Oblong has 400 normally-shaped residents. Transferrin is an iron carrier found in blood, and electrophoretic variation of this protein is determined by an autosomal codominant system. The citizens of Oblong were typed for their transferrin complements. The distribution of transferrin phenotypes was: 100 CC, 100 CD, and 200 DD. What is the frequency of the C allele?
1 2950Cystic fibrosis (CF) occurs with a frequency of about 1/2500 Caucasian newborns and is inherited as an autosomal recessive. A woman had an older sister die from complications of this disease. CF is not present among relatives of her husband. Both the woman and her husband have normal phenotypes. What is the chance this couple will have a CF child?
2246A blastomere was removed from an 8-cell human embryo, and its beta-globin gene was amplified by PCR. The beta-globin DNA was treated with an enzyme that cuts on either side of and within the normal allele (producing a small fragment), but not within the sickle cell allele (producing a large fragment). Electrophoresis of the treated DNA from the blastomere demonstrated the presence of both a large and small fragment derived from the beta-globin genes. How should you interpret this test?
2101
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Cystic fibrosis (CF) occurs with a frequency of about 1/2500 Caucasian newborns and is inherited as an autosomal recessive. A woman had an older sister die from complications of this disease. CF is not present among relatives of her husband. Both the woman and her husband have normal phenotypes. What is the chance this couple will have a CF child
In cats yellow is due to gene B and black to its allele b. These genes are located on the X chromosome (sex-linked). The heterozygous results in calico (tortoise shell). What kinds of offspring (sex & color) are expected from the cross: black male & calico female? Most calico males are sterile, why?
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The village of Oblong has 400 normally-shaped residents. Transferrin is an iron carrier found in blood, and electrophoretic variation of this protein is determined by an autosomal codominant system. The citizens of Oblong were typed for their transferrin complements. The distribution of transferrin phenotypes was: 100 CC, 100 CD, and 200 DD. What is the frequency of the C allele?
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