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Bio Informatics Interview Questions

What does the ultrametric property of a tree tell us about the evolutionary process?

1519

What is the difference in terms of connectivity between a scale free network and random network?

994

What two possibilities are there to describe how gene fragments may have evolved?

1181

Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ User sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?

1083

Suppose the Blast search returned 100 hits. Of these, 17 were false positives and we knew that there were 165 sequences in the database which should have returned a hit with our sequence. How many false negatives were there, and what is the sensitivity and selectivity of Blast in this instance?

1324

If a match from a sequence database search is reported to have an E-value of 0.0, should it be considered highly insignificant or highly significant?

2008

What is the idea behind ?weighting? sequences in the package CLUSTAL W for multiple alignment? How are these weights calculated?

1115

When a bicycle is in motion, the force of friction exerted by the ground on the two wheels is such that it acts a) In the backward direction on the front wheel and in the forward direction on the rear wheel. (b) In the forward direction on the front wheel and in the backward direction on the rear wheel. (c) In the backward direction on both the front and rear wheels. (d) In the backward direction on both the front and rear wheels.

26162

A certain radioactive element A, has a half life = t seconds. In (t/2) seconds the fraction of the initial quantity of the element so far decayed is nearly (a) 29% (b) 15% (c) 10% (d) 45%

8656

Which of the following plots would be a straight line ? (a) Logarithm of decay rate against logarithm of time (b) Logarithm of decay rate against logarithm of number of decaying nuclei (c) Decay rate against time (d) Number of decaying nuclei against time

3675

A radioactive element x has an atomic number of 100. It decays directly into an element y which decays directly into element z. In both processes a charged particle is emitted. Which of the following statements would be true? (a) y has an atomic number of 102 (b) y has an atomic number of 101 (c) z has an atomic number of 100 (d) z has an atomic number of 101

4521

If the sum of the roots of the equation ax2 + bx + c=0 is equal to the sum of the squares of their reciprocals then a/c, b/a, c/b are in (a) AP (b) GP (c) HP (d) None of these

7666

A man speaks the truth 3 out of 4 times. He throws a die and reports it to be a 6. What is the probability of it being a 6? (a) 3/8 (b) 5/8 (c) 3/4 (d) None of the above

22108

If cos2A + cos2B + cos2C = 1 then ABC is a (a) Right angle triangle (b) Equilateral triangle (c) All the angles are acute (d) None of these

9147

Image of point (3,8) in the line x + 3y = 7 is (a) (-1,-4) (b) (-1,4) (c) (2,-4) (d) (-2,-4)

7416

Un-Answered Questions { Bio Informatics }

Did shuffling of protein constituents occur between systems for multicomponent transport systems such as the atp-binding-cassette or complex protein secretion systems?

218

What does the ultrametric property of a tree tell us about the evolutionary process?

1519

what is a qi number?

1311

Describe the aim of microarray data analysis?

1525

What is the difference in terms of connectivity between a scale free network and random network?

994

Integrate 3x + 5 / (x3-x2-x+1)?

1254

Explain about the mass number of nuclear?

190

What is the input and outpit of a distance based algorithm?

1307

How to run DOCK 6 using cygwin?

5100

What is the secondary structure of intron ?

1219

can u give me an example of a project you were involved with that illustrates your interest and skills in bringing people together?

1197

How to find a sequence of dna molecule?

1191

What is protein sequencing?

200

Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?

1282

How to Insert Genomic DNA into yeast ?

1118