Why and when RRF is required to be known in RS Method? How is it helpful during

Why and when RRF is required to be known in RS Method? How is it helpful during method development?

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Why and when RRF is required to be known in RS Method? How is it helpful during method development?..

Answer / bandari

To Identify the impurity and exact value of result of particular impurity

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Why and when RRF is required to be known in RS Method? How is it helpful during method development?..

Answer / avtar singh

Relative response factor is to determine the impurity quantitatively for a the very precise method of Related substance......RRF is a ratio of response factor of impurity vs response factor of API ..
RF=area of peak/ conc. in mg/ml......

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Why and when RRF is required to be known in RS Method? How is it helpful during method development?..

Answer / rambabu vattikuti

In RS methodology RRF values establish for below points purpose
1) cost reduce purpose every time impurities not required for analysis and non availability of impurities use
2) RRF Values required for quantitative calculation and reporting purpose.

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