Why we are using the methanol in Kf titration?
- 6 Answers
- 19603 Views
- Reddy Labs, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / radheraman singh
Selection of methanol in Kf having following reason.
1 prevent the side reaction between pyridine and SO2.
2 Many compound are soluble in MeOH.
3 MeOH not absorbed moisture and having very less water content.
| Is This Answer Correct ? | 30 Yes | 3 No |
Answer / maulik
to prevent the side reaction of pyridine and so2
| Is This Answer Correct ? | 15 Yes | 2 No |
Answer / g.dasarath
during the titration py.so3 can reacts with h20 which varies
the stoichiometry of H2O and I2 from 1:1 to 2:1, to prevent
such side reactionexcessive anhydrous meoh is added as it
can react with py.so3 which lowers the concentration of py.so3
| Is This Answer Correct ? | 10 Yes | 2 No |
Answer / alexander
the methanol is necessary to carried out the reaction becz the bunchen reaction is occur in presence of lower alcohol and methanol is a lower alcohol(bunchen reaction- basic reaction on which karlfisher is based)
| Is This Answer Correct ? | 0 Yes | 1 No |
Answer / venkataramireddy.bh
ALL PHARMACEUTIAL COMPOUNDS ARE EASILY SOLUBLE IN
METHANOL,THE SELECTION OF METHANOLIS IT SHOULD CONTAIN LESS
WATERCONTENT
from vivimed
| Is This Answer Correct ? | 9 Yes | 12 No |
Answer / natraj kumar
ALL API's ARE SOLUBLE IN METHANOL,LOWEST COST AND WATER
CONTENT IS ALSO LESS.
| Is This Answer Correct ? | 2 Yes | 10 No |
How you can calculate pKa ?
when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.
why kf factor coming 0.5
why we are used 4,7,9,2 buffers for the ph calibration
4 Answers Aurobindo, Enaltec Labs,
what is the disso medium for tropsiun chloride
How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?
Why we use methanol as solvent in kf standardisation. Why not other solvent?
2 Answers Caplin Point, Epione Labs, Hetero,
Can we interpret accuracy from linearity in method validation?
How do you give training to a new chemist
in calibration of disintegration test apparatus why cycle limit is 28-32?
In UV we measure absorbance , how it is happend ? explain me
How to know HPLC column performance?
Organic Chemistry 
