what is sink condition in Dissolution?

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what is sink condition in Dissolution?..

Answer / ram

In general the dissolution medium volume should be 3-10
times the saturation solubulity of the drug. Sink
conditions means thd drug which goes in to the solution is
not effected by the drug which not dissolved.

Is This Answer Correct ?    192 Yes 43 No

what is sink condition in Dissolution?..

Answer / indra kumar gupta

In sink condition, the volume of Medium is more than 5-10 folds of its saturation point & in anyway it Drug will not reach to its saturation point.

Is This Answer Correct ?    57 Yes 18 No

what is sink condition in Dissolution?..

Answer / k.gopal rao

which should be able to dissolve the expected amount of drug released from a product. This ability of the medium to dissolve the expected amount of drug is known as a “sink condition"

Is This Answer Correct ?    23 Yes 6 No

what is sink condition in Dissolution?..

Answer / ganiraj6666

the volume of the medium is at least 3 times garter than the volume of the medium in which the drug gets saturated 

Is This Answer Correct ?    16 Yes 2 No

what is sink condition in Dissolution?..

Answer / ganesh parsewar

One of the requirements to conduct an appropriate drug
dissolution test is to use a sufficient volume of
dissolution medium, which should be able to dissolve the
expected amount of drug released from a product. This
ability of the medium to dissolve the expected amount of
drug is known as a “sink condition”.It is important to note
that a dissolution test should not be conducted in a volume
of the medium which would not dissolve the expected amount
of the drug completely and freely.

Is This Answer Correct ?    22 Yes 11 No

what is sink condition in Dissolution?..

Answer / apurva

sink condition is volume of medium greator than at least three times to form a saturated solution.with the help of sink condition we can fix vol of dissolution medium.as well as we can select dissolution medium for new drug substance.

Is This Answer Correct ?    5 Yes 1 No

what is sink condition in Dissolution?..

Answer / n bharth kumar

The concentration of drug at absorption site i.e.,GIT is more than in plasma level.....
It follows first order reaction(non linear graph)

Is This Answer Correct ?    11 Yes 16 No

what is sink condition in Dissolution?..

Answer / pankaj kumar

it is the condition at which the concentration of drug in
git is maintain greater then that of in plasma.

Is This Answer Correct ?    4 Yes 16 No

what is sink condition in Dissolution?..

Answer / ranjith

accordng to ficks first low c git is zero compare to c plasma .if have zero condition disslution is high

Is This Answer Correct ?    5 Yes 20 No

what is sink condition in Dissolution?..

Answer / honey

how much drug absorb its eliminated in same amount

Is This Answer Correct ?    5 Yes 37 No

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