Answer / kondhol asha

Dissolution is method for checking of amount of drug goes in to solution.
In-vitro Dissolution : is carried out outside the body it is done on artificial apparatus (Dissolution Apparatus) in which all conditions like pH, temperature, dissolution media etc are maintained same as that of human body.

In-vivo Dissolution: is carried out in human body the no of subject are given a testing drug & at time intervals blood is withdrawn from them & is checked for amount of drug present in it

now this two results are compared & graphs are plot bet. them to observe the similarity in the dissolution of drug by two methods.

Answer / srinu

bioavailability of drug in system(amount of drug reached in
systems)

Why we selecting 900 ml dissolution medium perticular drug as per I.P, USP?

2 Answers   Akums, Torrent Pharma,

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how quantitative stability studies are done?

0 Answers  

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What will be in case stability sampleWhich have batch but distribute in three country.In tath case< we can put the sample for all country, whenevr all have same temp(Zone)

5 Answers   Cipla, Wipro,

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which std you used for chemical calibration in dissolution?

2 Answers   Hetero, Reddy Labs,

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which is universal base for making suppositories?

2 Answers   Ranbaxy,

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What is NOEL?

1 Answers  

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For dissolution chemical calibration we use prednisone usp.. What is the lot number of prednisone? Label claim of prednisone ? How many samples in container generally?

6 Answers   Reddy Labs,

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is there any entrance exam conducted for the post of drug inspector and what is the usual time

0 Answers   Lupin,

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what is the composition of C18 column

2 Answers   Cipla, Deccan,

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How to check the integrity of Sieve, Screen, FBD Bag?

0 Answers  

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what is the exact diff betwen the uniformity of weight & uniformity of content?

3 Answers   Lupin,

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What is the difference between sonication and homozinization?

0 Answers  

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