IN pH CALIBRATION,CALIBRATION IS DONE FOR pH METER OR
ELECTRODE?HOW WILL YOU JUDGE THAT THE METER TO BE
CALIBRATED WITH 4,7,9.2 BUFFERS?EXPLAIN TEMPERATURE EFFECTS
ON pH.

Answer Posted / prabhu

Hi dear the calibration is also one of the system
suitability test,whether the system working satisfactory or
not physically so when you do the calibration for pH meter
with standard pH buffer solution (which is from NIST-it may
accurate solution for actual pH)and once if your instrument
has calibrated,you can cross verify your insrument against
those pH buffer solution (NIST) and the acceptable range is
+/- 0.02 then you can conclude for ?

once if temperature raises the pH will decrease and its not
all cases

Is This Answer Correct ?    18 Yes 5 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

what is mean by dissolution biowaiver study?

330


Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

308


all types of questions asked at the cipla interview

4139


What is the purpose of octyl silane columns?

3795


what is mean by nitrosamine impurities?

546






what is definition of validation? which components are followed give detail?

1832


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

1462


What is a difference between potency and purity?

647


Principle of single pan analytical balance

4606


What is the difference between chromatographic purity and related substances?

794


In Dissolution Test why limit is define Q+5% what is the role of +5%.

2580


For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?

3500


What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1148


what you do when compound having dwel wavelength?

285


What is the formula for relative diffrence for standard solution in solution stability in validation?

312