What is the difference between HPLC and GC?

Answer Posted / manisha

In hplc sample is partitioned between 2 phases and it is applicable for non volatile compounds whereas in cg adsorption phenomenon is taking place and mainly useful for volatile compounds.

Is This Answer Correct ?    10 Yes 11 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

if peak get problamatic then what require to do?

319


why are measure gas flow " ml " in Gas chromatography

1158


What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

312


some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2101


in which situation require to use paddle and basket?

293






How much is the standard area for glc analysis

1748


using gradient pressure in gas chromatography are not ?using gradient pressure why

2940


in gas chromatography what is the difference between gas flow rate and average linear velocity ?

1941


Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

2320


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

359


in api coa contains only process impurities and in product coa contains degradation impurities?

321


iam usig ph buffers merk. manually how to prepare ?

1781


UV and PDA detector, which have less signal to noise ratio?

647


why octanol used to determine the partition coefficient ?

1920


What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8310