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How you will select the runtime in HPLC for a drug in
method development.

Answer Posted / ankur dwivedi

There is no any thumb rule that the runtime should be 3
times than main peak, but also depends on the late eluting
impurities in compound; which should be confirmed at the
time of method development. Considering all these, the run
time should be selected.

Ankur Dwivedi
ZCL Chemicals, Ankleshwar

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