Why do we need GC instead of HPLC? or Why do we need HPLC
instead of GC?

Answer Posted / suresh

in hplc compounds are seperate based on adsorption, in this
technique less volatile compounds are seperated, column are
made from silica.


in gc compounds are seperate based on partition, high
volatile compounds are seperated, capiilary columns are used

Is This Answer Correct ?    2 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

How can the GC or HPLC method is selected to determine the impurity profile in drug product?

6848


How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

267


What are the primary considerations in extractables and Leachables ?

1773


what is the principle involved in turbidometry and nephelometry ?

3626


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1298






if you have given one product then how you determine the impurity in that?

280


What is similarity factor?

714


what is diffrence between specificity and selecivity?

297


How would you decide dissolution medium for NCE compound of class I drug

1690


how you fix the limits of impurities?

369


what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR

8408


what is %labelled amount in content uniformity of dosage unit and its calculation?

4611


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1785


How will u perform degradation study in detectors other thann PDA in HPLC Methodology

2012


How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2009