Answer Posted / pharmainterview

C8- C8 Carbon chain is attached to silica
c18- C18 Carbon chain is attached to silica.

There are many manufacturer who will prepare c8 or c18
column. Even though the basic concept is same for all,
there are some differences like
1.pore size
2.particle size
3.free silanol
4.end capping
5.silica purity etc

Based on our sample properties and suitability we can selct
a column after different trials.

Regards
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