Answer Posted / daljit singh randhawa

Theoretical plates(N):-

N = 5.55 x [RT/W]2

Here N = No. of Theoretical plates
RT = Retention Time
W = Peak width at half the hight of peak


Suppose RT of peak is 20 min. & Hight is 10 mm

Then W = 10/2 = 5


so N = 5.55 x [20/5]2

= 5.55 x [4]2
= 5.55 x 16 = 88.80

How can the GC or HPLC method is selected to determine the impurity profile in drug product?

7604

---

Why are use silicon oil mr?

1221

---

which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

2165

---

what is mean by extactable and leachable study?

1184

---

what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

4497

---

in api coa contains only process impurities and in product coa contains degradation impurities?

707

---

how to calculate elemental impurities?

1040

---

if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

991

---

How you develop a method in HPLC?

2626

---

all types of questions asked at the cipla interview

4689

---

which batch require to use for analytical method validation?

814

---

How to choose the which salt is suitable for mobilephase

3262

---

While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2874

---

why we use glass fiber filters use in some situation?

806

---

what is %labelled amount in content uniformity of dosage unit and its calculation?

5246

---